We derive a necessary and sufficient condition for HNN-extensions of cyclic subgroup separable groups with cyclic associated subgroups to be cyclic subgroup separable. Applying this, we explicitly characterize the residual finiteness and the cyclic subgroup separability of HNN-extensions of abelian groups with cyclic associated subgroups. We also consider these residual properties of HNN-extensions of nilpotent groups with cyclic associated subgroups.