We give a complete classification of umbilical submanifolds of arbitrary dimension and codimension of $\mathbb{S}^n\times \mathbb{R}$, extending the classification of umbilical surfaces in $\mathbb{S}^2\times \mathbb{R}$ by Souam and Toubiana as well as the local description of umbilical hypersurfaces in $\mathbb{S}^n\times \mathbb{R}$ by Van der Veken and Vrancken. We prove that, besides small spheres in a slice, up to isometries of the ambient space they come in a two-parameter family of rotational submanifolds whose substantial codimension is either one or two and whose profile is a curve in a totally geodesic $\mathbb{S}^1\times \mathbb{R}$ or $\mathbb{S}^2\times \mathbb{R}$, respectively, the former case arising in a one-parameter family. All of them are diffeomorphic to a sphere, except for a single element that is diffeomorphic to Euclidean space. We obtain explicit parametrizations of all such submanifolds. We also study more general classes of submanifolds of $\mathbb{S}^n\times \mathbb{R}$ and $\mathbb{H}^n\times \mathbb{R}$. In particular, we give a complete description of all submanifolds in those product spaces for which the tangent component of a unit vector field spanning the factor $\mathbb{R}$ is an eigenvector of all shape operators. We show that surfaces with parallel mean curvature vector in $\mathbb{S}^n\times \mathbb{R}$ and $\mathbb{H}^n\times \mathbb{R}$ having this property are rotational surfaces, and use this fact to improve some recent results by Alencar, do Carmo, and Tribuzy. We also obtain a Dajczer-type reduction of codimension theorem for submanifolds of $\mathbb{S}^n\times \mathbb{R}$ and $\mathbb{H}^n\times \mathbb{R}$.

We study Dupin hypersurfaces in $\mathbb R^5$ parametrized by lines of curvature, with four distinct principal curvatures. We characterize locally a generic family of such hypersurfaces in terms of the principal curvatures and four vector valued functions of one variable. We show that these vector valued functions are invariant by inversions and homotheties.