We solve several multi-parameter families of binomial Thue equations of arbitrary degree; for example, we solve the equation \[ 5^u x^n-2^r 3^s y^n= \pm 1, \] in non-zero integers $x$, $y$ and positive integers $u$, $r$, $s$ and $n \geq 3$. Our approach uses several Frey curves simultaneously, Galois representations and level-lowering, new lower bounds for linear forms in $3$ logarithms due to Mignotte and a famous theorem of Bennett on binomial Thue equations.