We introduce the fundamental group ${\mathcal F}(A)$ of a simple $\sigma$-unital $C^*$-algebra $A$ with unique (up to scalar multiple) densely defined lower semicontinuous trace. This is a generalization of ``Fundamental Group of Simple $C^*$-algebras with Unique Trace I and II'' by Nawata and Watatani. Our definition in this paper makes sense for stably projectionless $C^*$-algebras. We show that there exist separable stably projectionless $C^*$-algebras such that their fundamental groups are equal to $\mathbb{R}_+^\times$ by using the classification theorem of Razak and Tsang. This is a contrast to the unital case in Nawata and Watatani. This study is motivated by the work of Kishimoto and Kumjian.

We introduce and investigate using Hilbert modules the properties of the {\em Fourier algebra} $A(G)$ for a locally compact groupoid $G$. We establish a duality theorem for such groupoids in terms of multiplicative module maps. This includes as a special case the classical duality theorem for locally compact groups proved by P. Eymard.